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KMID : 0986520150150040086
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Korean Journal of Endoscrine Surgery
2015 Volume.15 No. 4 p.86 ~ p.92
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Prediction of Nodal Metastasis by the AMES Scoring System in Patients with Papillary Thyroid Cancer
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Lee Youn-Ju
Kim Je-Ryong
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Abstract
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Purpose: We assessed the prognostic value of AMES to determine the extent of surgery in PTC patients, and compared AMES score usefulness and accuracy with [18F] FDG PET/CT.
Methods: We conducted a review of data from a single center and a single surgeon, who treated 341 patients with PTC with total thyroidectomy and prophylactic bilateral CLN dissection at a tertiary referral center, Chungnam National University Hospital, between 2001 and 2012.
Results: In multivariate analysis, the rate of CLN metastasis was considerably higher in PTC patients with the higher AMES score (odds ratio [OR], 1.718; 95% confidence interval [CI], 1.073∼2.752), higher SUV of the CLN (＞0) (OR, 6.525; CI, 3.184∼13.371), higher SUV of the tumor (＞4.3) (OR, 1.855; CI, 1.065∼3.231).
Conclusion: The AMES score is helpful in deciding whether to perform a CLN dissection, as there is a strong association between the AMES score and CLN metastasis. This high predictive value of CLN metastasis can help determine the extent of PTC surgery while considering the cost and effort.
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KEYWORD
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Papillary thyroid carcinoma, Central lymph node, AMES, Lymph node metastasis, Positron emission tomography-computed tomography
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